SYNTHESIS AND REACTIONS OF SOME NEW PYRROLYLTHIENO[2,3-d]QUINOXALINE AND PYRROLOPYRAZINOTHIENOQUINOXALINES

©2012 Ahmed A. Geies, Yasser A. Elossaily^#, and Osama Sh. Moustafa

^#E-mail: [email protected]

Chemistry Department, Faculty of Science, Assiut University, Assiut 71516, Egypt

Abstract. The synthesis of 3-pyrrolyl-2-substituted thieno[2,3-b]quinoxalines from the precursor 3-amino derivatives are described. Synthesized compounds were subjected to reactions with other reagents to synthesize polyfused heterocyclic incorporated thienoquinoxaline moiety. Some of the synthesized compounds were screened for their antibacterial and antifungal activities.

Key words: Pyrrolylthienoquinoxaline, Pyrrolopyrazinothienoquinoxalines, Pyrrolyl triazolylthienoquinoxaline, Synthesis, Antimicrobial Activity.

Биоорг.химия 2012, 38 (5): 597-603