Study of Various Pyridazine and Phthalazine Drugs with Diverse Therapeuticallyand Agrochemically Activities

Mohd Imran^a and Mohammad Asif^{b, 1}

¹E-mail: [email protected]

^aDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Northern Border University, Rafha 91911, PO Box 840, Saudi Arabia;
^bDepartment of Pharmacy, Himalayan Institute of Pharmacy and Research, Dehradun, (Uttarakhand), 248007, India

Received 08.02.2020; revised 04.04.2020; accepted 08.04.2020

DOI: 10.1134/S1068162020050167

Abstract––Pyridazines hold considerable interest relative to pharmacologically active molecules. The pyridazine compounds are exhibited different types of pharmacological activities. The various pyridazine drugs are shown phosphodiestrase (PDE) inhibitor, positive inotropic, vasodilation, analgesic, antiiflamatory, antimicrobial, antidepressant, antipsychotic, antianxiety, antifeeedant, herbicidal, insecticidal, plant growth regulatory, molluscicidal and other biological and agrochemical activities. Pyridazine derivatives focused consideration because of their effortless fuctionalization at various ring positions, which creates them striking compounds for designing and progress of the new pyridazine drugs in future.

Keywords: biological activities, drugs, pyridazines, structural feature
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Полный текст статьи печатается в переводной версии журнала Russian Journal of Bioorganic Chemistry, V.46, Issue 5, P. 745-767 (Springer)